FDA finds little evidence that the generic drug leucovorin can help people with autism

PBS NewsHour
by Matthew Perrone, Associated Press
March 10, 2026
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2 min read

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The Bottom Line

FDA finds little evidence that the generic drug leucovorin helps people with autism.

How This Affects You

If you or a family member with autism are considering leucovorin, the FDA states there is minimal evidence of its efficacy for autism.

AI Summary

The Food and Drug Administration (FDA) has found minimal evidence supporting the use of the generic drug leucovorin for individuals with autism. According to FDA officials, current data indicates the drug's efficacy is limited to patients diagnosed with a specific genetic disorder. This finding suggests the broader application of leucovorin for autism lacks regulatory support. The FDA's stance clarifies the approved indications for the drug, potentially influencing prescribing practices and future research directions.

What's Being Done

The FDA has found minimal evidence supporting the use of leucovorin for individuals with autism.

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