US and Iran: A brief history of how decades of mistrust and bad blood led to open warfare

The Conversation
by Jeffrey Fields, Professor of the Practice of International Relations, USC Dornsife College of Letters, Arts and Sciences
April 4, 2026
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3 min read

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Decades of US-Iran mistrust and conflict created conditions for current open warfare, though some historical moments offered reconciliation opportunities.

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U.S. and Iranian forces are now engaged in open warfare, with American bombs striking Iran and Tehran responding by attacking targets across the Persian Gulf while restricting transit through the Strait of Hormuz. The conflict stems from decades of animosity dating to 1953, when the CIA and British intelligence overthrew Prime Minister Mohammed Mossadegh and installed a Western-friendly successor, followed by U.S. support for the repressive Shah's 25-year rule. The tensions escalated sharply after Iranian students seized the U.S. Embassy in Tehran in November 1979, triggering economic sanctions and a severing of diplomatic relations that persist today. Since 1984, the State Department has designated Iran a "state sponsor of terrorism," alleging the government provides training, money, and weapons to terrorist organizations. The article traces how these historical grievances—rooted in the 1953 coup and the Shah's brutal dictatorship—set the stage for the current military confrontation.

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